A defendant’s response to the charges made against them, it can be any of the following: guilty; not guilty; or nolo contendere.
Merriam-Webster Online Dictionary
plea (noun)1.
 a legal suit or action
2.
  an allegation made by a party in support of a cause  as
a)  an allegation of fact  - compare demurrer
b)  (1)  a defendant's answer to a plaintiff's declaration in common-law practice
(2)  an accused person's answer to a charge or indictment in criminal practice
c)   a plea of guilty to an indictment 
3.
something offered by way of excuse or justification  - left early with the plea of a headache
4.
an earnest entreaty   - appeal their plea for understanding must be answered apology
Merriam-Webster Online Thesaurus
plea (noun)1.
an earnest request
SYNONYMS:
adjuration, appeal, conjuration, cry, desire, entreaty, petition, pleading, prayer, solicitation, suit, suppliance, supplicationRELATED WORDS:
application, requisition; call, claim, demand, insistence2.
an explanation that frees one from fault or blame
SYNONYMS:
alibi, apology, defense, justification, plea, reasonRELATED WORDS:
color, guise, pretense ( pretence), pretext, rationale, rationalization, vindication, whitewash; cop-out, out; acknowledgment ( acknowledgement), atonement, confession; extenuation, palliation